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小分子

IDE2

Activin/BMP/TGF-β pathway activator

概要
技术资料
数据及文献

概要

Inducer of definitive endoderm 2 (IDE2) induces differentiation of mouse or human pluripotent stem cells (PSCs) by activating SMAD2 phosphorylation and NODAL expression (Borowiak et al.). At EC₅₀ = 223nM, SOX17 expression was induced in mouse ES cells.

DIFFERENTIATION
· Induces definitive endoderm from mouse or human ES cells in the absence of Activin A, NODAL, or feeder cells (Borowiak et al.).

技术资料

Document Type 产品名称 Catalog # Lot # 语言
Product Information Sheet IDE2 72522, 72524 All English
Safety Data Sheet IDE2 72522, 72524 All English

数据及文献