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概要
Compound E is a potent, cell-permeable, selective inhibitor that blocks the cleavage of both gamma-secretase and the Notch intracellular domain with similar IC50 values, ranging from 0.24 to 0.37 nM (Beher et al.; Seiffert et al.).
DIFFERENTIATION
· Inhibits growth, differentiation, and motility of neuroblastoma cells (Ferrari-Toninelli et al.).
· Accelerates the differentiation of human embryonic stem cells into primitive neural stem cells (Li et al.).
DIFFERENTIATION
· Inhibits growth, differentiation, and motility of neuroblastoma cells (Ferrari-Toninelli et al.).
· Accelerates the differentiation of human embryonic stem cells into primitive neural stem cells (Li et al.).
技术资料
| Document Type | 产品名称 | Catalog # | Lot # | 语言 |
|---|---|---|---|---|
| Product Information Sheet | Compound E | 73952, 73954 | All | English |
| Safety Data Sheet | Compound E | 73952, 73954 | All | English |
