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概要
L755507 is a potent and selective β-3 adrenergic receptor agonist that demonstrates > 440-fold selectivity over β-1 and β-2 binding (EC50 = 0.43, 580, and > 10,000 nM for activation of cloned human β-3-, β-2-, and β-1-adrenoreceptors, respectively; Parmee et al.).
DIFFERENTIATION
· Stimulates lipolysis in human white adipose tissue (Fisher et al.).
GENE EDITING
· Improves the efficiency of homology-directed repair in human induced-pluripotent stem cells following CRISPR editing (Yu et al.).
METABOLISM
· Increases metabolism in rhesus monkeys (Fisher et al.).
DIFFERENTIATION
· Stimulates lipolysis in human white adipose tissue (Fisher et al.).
GENE EDITING
· Improves the efficiency of homology-directed repair in human induced-pluripotent stem cells following CRISPR editing (Yu et al.).
METABOLISM
· Increases metabolism in rhesus monkeys (Fisher et al.).
技术资料
| Document Type | 产品名称 | Catalog # | Lot # | 语言 |
|---|---|---|---|---|
| Product Information Sheet 1 | L755507 | 73992, 73994 | All | English |
| Product Information Sheet 2 | L755507 | 73992, 73994 | All | English |
| Safety Data Sheet | L755507 | 73992, 73994 | All | English |
