Anti-Mouse CD19 Antibody, Clone 1D3_产品中心_北京砺达辰生物科技有限公司

抗体

Anti-Mouse CD19 Antibody, Clone 1D3

Rat monoclonal IgG2a antibody against mouse CD19

概要

技术资料

数据及文献

概要

The 1D3 antibody reacts with mouse CD19, an ~95 kDa type 1 transmembrane glycoprotein expressed on the surface of B cells throughout all stages of development, from early pre-B cells to plasma cells. Expression is down-regulated but persists in terminally differentiated plasma cells. CD19 is also found on follicular dendritic cells. By associating with CD21 and CD81, CD19 functions as a co-receptor for the B cell receptor and is involved in B cell activation and differentiation. Activation of CD19 is accompanied by phosphorylation of the cytoplasmic domain, which promotes binding to kinases and the induction of intracellular signaling cascades. Mutations in CD19 can result in severe immunodeficiency syndromes. Clone 1D3 recognizes the same epitope as clone 6D5 in cross-competition assays.

技术资料

Document Type	产品名称	Catalog #	Lot #	语言
Product Information Sheet	Anti-Mouse CD19 Antibody, Clone 1D3	60112, 60112.1	All	English
Product Information Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, APC	60112AZ, 60112AZ.1	All	English
Product Information Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, Biotin	60112BT, 60112BT.1, 60112BT.2	All	English
Product Information Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, FITC	60112FI, 60112FI.1, 60112FI.2	All	English
Product Information Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, PE	60112PE, 60112PE.1	All	English
Product Information Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, PerCP-Cy5.5	60112PS, 60112PS.1	All	English
Safety Data Sheet	Anti-Mouse CD19 Antibody, Clone 1D3	60112, 60112.1	All	English
Safety Data Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, APC	60112AZ, 60112AZ.1	All	English
Safety Data Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, Biotin	60112BT, 60112BT.1, 60112BT.2	All	English
Safety Data Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, FITC	60112FI, 60112FI.1, 60112FI.2	All	English
Safety Data Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, PE	60112PE, 60112PE.1	All	English
Safety Data Sheet	Anti-Mouse CD19 Antibody, Clone 1D3, PerCP-Cy5.5	60112PS, 60112PS.1	All	English

数据及文献

Data

Figure 1. Data for Unconjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD19 Antibody, Clone 1D3, followed by a mouse anti-rat IgG2a antibody, FITC (filled histogram), or a rat IgG2a, kappa isotype control antibody followed by a mouse anti-rat IgG2a antibody, FITC (solid line histogram).

Figure 2. Data for APC-Conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD19 Antibody, Clone 1D3, APC (filled histogram) or a rat IgG2a, kappa isotype control antibody, APC (solid line histogram).

Figure 3. Data for Biotin-Conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD19 Antibody, Clone 1D3, Biotin, followed by streptavidin (SAV) APC (filled histogram), or a biotinylated rat IgG2a, kappa isotype control antibody followed by SAV APC (solid line histogram).

Figure 4. Data for FITC-Conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD19 Antibody, Clone 1D3, FITC (filled histogram) or a rat IgG2a, kappa isotype control antibody, FITC (solid line histogram).

Figure 5. Data for PE-Conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD19 Antibody, Clone 1D3, PE (filled histogram) or a rat IgG2a, kappa isotype control antibody, PE (solid line histogram).

Figure 6. Data for PerCP-Cy55-Conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD19 Antibody, Clone 1D3, PerCP-Cy5.5 (filled histogram) or a rat IgG2a, kappa isotype control antibody, PerCP-Cy5.5 (solid line histogram).