当前位置:首页 > 产品中心 > 抗体

抗体

Anti-Human HLA-DR Antibody, Clone LN3

Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR

概要
技术资料
数据及文献

概要

The LN3 antibody reacts with the HLA-DR antigen, a major histocompatibility complex (MHC) class II antigen encoded within the human leukocyte antigen (HLA) complex on chromosome 6. HLA-DR is a heterodimeric transmembrane glycoprotein composed of one α (36 kDa) and one β (27 kDa) subunit. MHC class II plays a central role in the presentation of antigen-derived peptides to CD4+ T cells, along with CD3/TCR and CD4. HLA-DR is primarily expressed on the surface of antigen presenting cells, including B cells, dendritic cells, monocytes, macrophages, thymic epithelial cells, and activated T cells.

数据及文献

Data

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, followed by an anti-mouse IgG2b antibody, PE (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11 (Catalog #60072), followed by an antimouse IgG2b antibody, PE (solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, FITC (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, FITC (Catalog #60072FI; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, PE (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, PE (Catalog #60072PE; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human HLA-DR Antibody, Clone LN3, Alexa Fluor® 488 (filled histogram), or Mouse IgG2b, kappa Isotype Control Antibody, Clone MPC-11, Alexa Fluor® 488 (Catalog #60072AD; solid line histogram).