Anti-Human CD68 Antibody, Clone Y1/82A_产品中心_北京砺达辰生物科技有限公司

抗体

Anti-Human CD68 Antibody, Clone Y1/82A

Mouse monoclonal IgG2b antibody against human CD68

概要

技术资料

数据及文献

概要

The Y1/82A antibody reacts with human CD68, an ~110 kDa type 1 transmembrane glycoprotein and member of the sialomucin, LAMP and scavenger receptor families. The heavily glycosylated extracellular domain of CD68, which contains a praline-rich spacer region separating mucin and LAMP domains, binds low-density lipoprotein and certain lectins and selectins, though the function of CD68 remains unclear. CD68 is highly expressed in lysosomes, endosomes and cytoplasmic granules, and more weakly on the surface of macrophages, monocytes, neutrophils, basophils, dendritic cells and NK cells. It has also been detected in the cytoplasm of γ/δ T cells, LAK cells, fibroblasts, endothelial cells and subsets of B cells and hematopoietic progenitors, as well as in various non-hematopoietic tissues such as liver and kidney. The Y1/82A antibody recognizes an epitope distinct from those of antibody clones Y2/131, EBM11, Ki-M6 and KP1. Y1/82A is reportedly more specific for monocytes and macrophages than KP1.

技术资料

Document Type	产品名称	Catalog #	Lot #	语言
Product Information Sheet	Anti-Human CD68 Antibody, Clone Y1/82A	60105, 60105.1	All	English
Product Information Sheet	Anti-Human CD68 Antibody, Clone Y1/82A, Alexa Fluor® 488	60105AD, 60105AD.1	All	English
Product Information Sheet	Anti-Human CD68 Antibody, Clone Y1/82A, APC	60105AZ, 60105AZ.1	All	English
Product Information Sheet	Anti-Human CD68 Antibody, Clone Y1/82A, Biotin	60105BT	All	English
Product Information Sheet	Anti-Human CD68 Antibody, Clone Y1/82A, FITC	60105FI, 60105FI.1	All	English
Product Information Sheet	Anti-Human CD68 Antibody, Clone Y1/82A, PE	60105PE, 60105PE.1	All	English
Safety Data Sheet	Anti-Human CD68 Antibody, Clone Y1/82A	60105, 60105.1	All	English
Safety Data Sheet	Anti-Human CD68 Antibody, Clone Y1/82A, APC	60105AZ, 60105AZ.1	All	English
Safety Data Sheet	Anti-Human CD68 Antibody, Clone Y1/82A, Biotin	60105BT	All	English
Safety Data Sheet	Anti-Human CD68 Antibody, Clone Y1/82A, FITC	60105FI, 60105FI.1	All	English
Safety Data Sheet	Anti-Human CD68 Antibody, Clone Y1/82A, PE	60105PE, 60105PE.1	All	English

数据及文献

Data

Figure 1. Data for Unconjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD3e Antibody, Clone 145-2C11, followed by anti-hamster (Armenian) IgG, FITC (filled histogram) or an Armenian hamster IgG isotype control antibody followed by anti-hamster (Armenian) IgG, FITC (open histogram).

Figure 2.Data for Alexa Fluor® 488-conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD3e Antibody, Clone 145-2C11, Alexa Fluor® 488 (filled histogram) or an Armenian hamster IgG Alexa Fluor® 488 isotype control antibody (solid line histogram).

Figure 3. Data for APC-conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD3e Antibody, Clone 145-2C11, APC (filled histogram) or an Armenian hamster IgG APC isotype control antibody (solid line histogram).

Figure 4. Data for Biotin-conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD3e Antibody, Clone 145-2C11, Biotin followed by streptavidin (SAV) APC (filled histogram) or an Armenian hamster IgG biotin isotype control antibody followed by SAV APC (solid line histogram).

Figure 5. Data for FITC-conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD3e Antibody, Clone 145-2C11, FITC (filled histogram) or an Armenian hamster IgG FITC isotype control antibody (solid line histogram).

Figure 6. Data for PE-conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD3e Antibody, Clone 145-2C11, PE (filled histogram) or an Armenian hamster IgG PE isotype control antibody (solid line histogram).

Figure 7. Data for PerCP-Cy5.5 Conjugated

Flow cytometry analysis of C57BL/6 mouse splenocytes labeled with Anti-Mouse CD3e Antibody, Clone 145-2C11, PerCP-Cy5.5 (filled histogram) or an Armenian hamster IgG isotype control antibody, PerCP-Cy5.5 (solid line histogram).