Anti-Human CD38 Antibody, Clone HIT2_产品中心_北京砺达辰生物科技有限公司

抗体

Anti-Human CD38 Antibody, Clone HIT2

Mouse monoclonal IgG1 antibody against human, chimpanzee, horse CD38

概要

技术资料

数据及文献

概要

The HIT2 antibody reacts with CD38, an ~45 kDa type II transmembrane glycoprotein expressed by many cell types, especially leukocytes. CD38 is an ectoenzyme (ADP-ribosyl hydrolase) with both cyclase and hydrolase activities, whereby it mediates lymphocyte activation, adhesion and metabolism. CD31 is a known ligand for the receptor. In humans, CD38 is expressed by the majority of hematopoietic cells at levels which vary according to the differentiation and activation status of the cells. It is highly expressed on activated T and B cells and plasma cells, and is also found at high levels in several tissues, including brain, kidney, liver, ovary, pancreas, placenta, testis, and some types of cancerous tissue.

This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Human CD138 Positive Selection Kit II (Catalog #1877) and EasySep™ Human Whole Blood and Bone Marrow CD138 Positive Selection Kit II (Catalog #17887).

技术资料

Document Type	产品名称	Catalog #	Lot #	语言
Product Information Sheet	Anti-Human CD38 Antibody, Clone HIT2	60014	All	English
Product Information Sheet	Anti-Human CD38 Antibody, Clone HIT2, Alexa Fluor® 488	60014AD, 60014AD.1	All	English
Product Information Sheet	Anti-Human CD38 Antibody, Clone HIT2, APC	60014AZ, 60014AZ.1	All	English
Product Information Sheet	Anti-Human CD38 Antibody, Clone HIT2, Biotin	60014BT	All	English
Product Information Sheet	Anti-Human CD38 Antibody, Clone HIT2, FITC	60014FI, 60014FI.1	All	English
Product Information Sheet	Anti-Human CD38 Antibody, Clone HIT2, PE	60014PE, 60014PE.1	All	English
Safety Data Sheet	Anti-Human CD38 Antibody, Clone HIT2	60014	All	English
Safety Data Sheet	Anti-Human CD38 Antibody, Clone HIT2, Alexa Fluor® 488	60014AD, 60014AD.1	All	English
Safety Data Sheet	Anti-Human CD38 Antibody, Clone HIT2, APC	60014AZ, 60014AZ.1	All	English
Safety Data Sheet	Anti-Human CD38 Antibody, Clone HIT2, Biotin	60014BT	All	English
Safety Data Sheet	Anti-Human CD38 Antibody, Clone HIT2, FITC	60014FI, 60014FI.1	All	English
Safety Data Sheet	Anti-Human CD38 Antibody, Clone HIT2, PE	60014PE, 60014PE.1	All	English

数据及文献

Data

Figure 1. Data for Unconjugated

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD38 Antibody, Clone HIT2, followed by Goat Anti-Mouse IgG (H+L) Antibody, Polyclonal, FITC (Catalog #60138FI) (filled histogram), or a mouse IgG1, kappa isotype control antibody followed by Goat Anti-Mouse IgG (H+L) Antibody, Polyclonal, FITC (solid line histogram).

Figure 2. Data for Alexa Fluor® 488-Conjugated

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD38 Antibody, Clone HIT2, Alexa Fluor® 488 (filled histogram) or a mouse IgG1, kappa Alexa Fluor® 488 isotype control antibody (solid line histogram).

Figure 3. Data for PE-Conjugated

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD38 Antibody, Clone HIT2, PE (filled histogram) or a mouse IgG1, kappa PE isotype control antibody (solid line histogram).

Figure 4. Data for APC-Conjugated

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD38 Antibody, Clone HIT2, APC (filled histogram) or a mouse IgG1, kappa isotype control antibody, APC (solid line histogram).

Figure 5. Data for Biotin-Conjugated

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD38 Antibody, Clone HIT2, Biotin followed by streptavidin (SAV) APC (filled histogram), or a biotinylated mouse IgG1, kappa isotype control antibody followed by SAV APC (solid line histogram).

Figure 6. Data for FITC-Conjugated

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs) labeled with Anti-Human CD38 Antibody, Clone HIT2, FITC (filled histogram) or a mouse IgG1, kappa isotype control antibody, FITC (solid line histogram).